Two errors from his favourite backhand and a double-fault opened the door for Tsonga to break back and the Frenchman then swept through the final three games, sealing the 16th five-set victory of his career with a textbook serve and volley winner.
The volatile 17th seed had a quiet evening by his standards in his opening match on Monday, with just the one violation for unsportsmanlike behaviour when he asked spectator, in no uncertain terms, to be quiet while he was serving.
IMAGES of the all the action from Day 1 of the Australian Open played at Melbourne Park on Monday
He leads the men's seedings ahead of defending champ Roger Federer, with Bulgarian Grigor Dimitrov seeded third.
In a sensational turnaround, the unseeded Frenchman toppled the world number six from Croatia 1-6, 6-3, 6-2 in a gripping semi-final encounter.
France won their 10th Davis Cup title when Lucas Pouille crushed Steve Darcis 6-3, 6-1, 6-0 to give the hosts a 3-2 victory in the final against neighbours Belgium on Sunday.
David Goffin put the visitors ahead by beating Lucas Pouille in the opening singles before Jo-Wilfried Tsonga levelled for 1-1 when he defeated Steve Darcis in the second singles on Friday.
Belgium's chances of claiming a maiden Davis Cup title against hosts France remained intact after Friday's opening singles, in which David Goffin made a huge impression, were tied 1-1.
The tie will be played on a hard court indoor surface with the roof closed.
Jo-Wilfried Tsonga beat Dusan Lajovic 2-6, 6-2, 7-6(5), 6-2 to give France an unassailable 3-1 lead against Serbia and book their place in the Davis Cup final.
Ramkumar Ramanathan fetched the crucial win but Yuki Bhambri made the day memorable even in defeat as India and Canada shared the honours on day one of the Davis Cup World Group Play-off tie, in Edmonton.
'You'd also be wrong if you tried to lump me in the same category as Bernard Tomic'
Ramkumar to play opening singles tie against Schnur, Yuki takes on Shapovalov on day 1
Shapovalov made the world take note of him with his shock win over Rafael Nadal at the Montreal Masters. He then became the youngest player to reach the fourth round of the US Open, only his second Grand Slam, last week.
Both men are 31 years old but have little else in common.
Rafael Nadal was at his awe-inspiring best as he recovered from a first set wobble to crush Juan Martin del Potro 4-6, 6-0, 6-3, 6-2 in the US Open semi-finals on Friday and move within reach of a 16th Grand Slam title.
Canada named rising star and world number 69 Denis Shapovalov in its squad to take on India in the upcoming Davis Cup World Group Play-off tie, scheduled in Edmonton from September 15.
The charismatic 18-year-old Canadian has infatuated the New York crowds with his skill and on court panache that has made him the youngest man to make it into the fourth round of the US Open since American Michael Chang in 1989.
Denis Shapovalov may not be old enough to drink in New York but is quickly becoming the toast of the Big Apple and the 18-year-old Canadian will again have a chance to light up the U.S. Open when he takes on Briton Kyle Edmund.
Rediff.com presents the early surprises at the year's final Grand Slam
IMAGES from Day 3 of the US Open in New York on Wednesday.
Maria Sharapova will be back in the US Open spotlight on Wednesday hoping she can come up with a winning encore to her electrifying first round victory over second seed Simona Halep.
US Open, the final Grand Slam of the season, starts Monday, August 28, at Flushing Meadows in New York.
A day after celebrating his 36th birthday, Federer played the aggressive game that has propelled him to five titles, including two grand slams, this year, attacking the net and rocketing second serves.
Eugenie Bouchard's mid-season nosedive continued on Tuesday as the Canadian was swept aside 6-3 6-4 by Croatian qualifier Donna Vekic despite having home advantage and the backing of an excited crowd in a first round clash at the Rogers Cup.
PHOTOS from day four of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Saturday
Wimbledon was invaded by thousands of flying ants on Wednesday, causing much annoyance to players, officials and ticket holders alike - but there was little anyone could do to drive out the pests.
Images from all the action from Day 1 of the Wimbledon on Monday.
The Rafael Nadal Tennis Academy, which opened last autumn on the Spanish island of Mallorca, is charging kids 56,000 euros ($62,000) a year for tennis lessons and school.
British player Dan Evans has been provisionally suspended after admitting on Friday that he had failed a doping test for cocaine at the Barcelona Open in April.
The Frenchman, seeded five, had no answer to left-hander Muller's swinging serve as he bowed out 6-4, 6-4.
Tsonga outplayed his compatriot Adrian Mannarino 6-2, 6-2 in the opening round of the traditional Wimbledon warm-up event in his first match since suffering a four-set defeat by little-known Argentine Renzo Olivo at Roland Garros.
French federation president Bernard Giudicelli has hit out at the country's male players after their disappointing run at Roland Garros, saying they lacked physical strength and grit.
France's wait for a men's singles champion at Roland Garros will stretch into a 35th year, and three-times champion Mats Wilander says their current crop of stars are running out of time.
Images from Day 4 of the French Open matches played at Roland Garros in Paris on Wednesday
Jo-Wilfried Tsonga polished his preparation for the French Open in style by claiming his maiden claycourt title, beating Czech Tomas Berdych 7-6(2), 7-5 in the Lyon Open final on Saturday.
Mischa Zverev took some of the limelight back from younger brother Alexander when he beat second seed Kei Nishikori to reach the Geneva Open final on Friday.
Penpix of the top men's contenders at the 2017 French Open:
Home favourite Jo-Wilfried Tsonga sauntered into the semi-finals of the Lyon Open with a 6-0, 6-4 victory over Russian youngster Karen Khachanov on Thursday.